Identification

Numero CAS

71-63-6

Nom scientifique (FR)

Digitoxine

Nom scientifique (EN)

3-[(3S,5R,8R,9S,10S,13R,14S,17R)-3-[(2R,4S,5S,6R)-5-[(4R,5S,6R)-5-[(4S,5S,6R)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

Autres dénominations scientifiques (Autre langues)

digitoxin ; lanatoxin ; myodigin ; purodigin ; purpurid ; tardigal ; digimed ; ditaven ; natigal ; digitaline nativelle ; digitoxigenin tridigitoxoside ; crystalline ; mono-glycocard ; digicor ; digitrin ; digipural ; coramedan ; asthenthilo ; digisidin ; digimerck ; digilong ; cardigin ; acedoxin ; glucodigin ; cristapurat ; carditoxin ; digitophyllin ; crystalline digitalin ; card-20(22)-enolide, 3-[[o-2,6-dideoxy-beta-d-ribo-hexopyranosyl-(1->4)-o-2,6-dideoxy-beta-d-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-d-ribo-hexopyranosyl]oxy]-14-hydroxy-, (3beta,5beta)- ; (3beta,5beta)-3-{[2,6-dideoxy-beta-d-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-d-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-d-ribo-hexopyranosyl]oxy}-14-hydroxycard-20(22)-enolide ; 5beta,20(22)-cardenolide-3beta,14-diol-3-(o-2,6-dideoxy-beta-d-ribo-hexopyranosyl-[1->4]-o-2,6-dideoxy-beta-d-ribo-hexopyranosyl-[1->4]-2,6-dideoxy-beta-d-ribo-hexopyranosyl)oxy ; 3beta-[2,6-dideoxy-beta-d-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-d-ribo-hexopyranosyl-(1->4)-2,6-dideoxy-beta-d-ribo-hexopyranosyloxy]-14-hydroxy-5beta-card-20(22)-enolide ; digitaline ; 4-[(1s,2s,5s,7r,10r,11s,14r,15r)-5-{[(2r,4s,5s,6r)-5-{[(2s,4s,5s,6r)-5-{[(2s,4s,5s,6r)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-11-hydroxy-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-14-yl]-2,5-dihydrofuran-2-one ; 4-[(3s,5r,8r,9s,10s,13r,14s,17r)-3-[(2r,4s,5s,6r)-5-[(2s,4s,5s,6r)-5-[(2s,4s,5s,6r)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-5h-furan-2-one ; 3-[(3s,5r,8r,9s,10s,13r,14s,17r)-3-[(2r,4s,5s,6r)-5-[(2s,4s,5s,6r)-5-[(2s,4s,5s,6r)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-4-hydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2h-furan-5-one ; glucokinin ; 3-[(3s,5r,8r,9s,10s,13r,14s,17r)-3-[(2r,4s,5s,6r)-5-[(2s,4s,5s,6r)-5-[(2s,4s,5s,6r)-4,5-dihydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-4-hydroxy-6-methyl-tetrahydropyran-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2h-furan-5-one ; -2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadecan-14-yl]-2,5-dihydrofuran-2-one ; 4-[(1s,2s,5s,7r,10r,11s,14r,15r)-5-{[(2r,4s,5s,6r)-5-{[(2s,4s,5s,6r)-5-{[(2s,4s,5s,6r)-4,5-dihydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-4-hydroxy-6-methyloxan-2-yl]oxy}-11-hydroxy ; 4-((1s,2s,5s,11s,7r,10r,14r,15r)-5-{5-[5-((2s,4s,5s,6r)-4,5-dihydroxy-6-methyl (2h-3,4,5,6-tetrahydropyran-2-yloxy))(4s,5s,2r,6r)-4-hydroxy-6-methyl(2h-3,4,5 ,6-tetrahydropyran-2-yloxy)](4s,5s,2r,6r)-4-hydroxy-6-methyl(2h-3,4,5,6-tetrah ydropyran-2-yloxy)}-11-hydroxy-2,15-dimethyltetracyclo[8.7.0.0.0]h eptadec-14-yl)-5-hydrofuran-2-one ; crystodigin (tn) ; digitoxoside ; digitoxinum ; digitoksin ; crystodigin

Code EC

-

Code SANDRE

-

Numéro CIPAC

-

Formule chimique brute

\(\ce{ C41H64O13 }\)

Code InChlKey

WDJUZGPOPHTGOT-DOMBIWABSA-N

Code SMILES

C[C@@H]1[C@H]([C@H](CC(O1)O[C@@H]2[C@H](OC(C[C@H]2O)O[C@@H]3[C@H](O[C@H](C[C@@H]3O)O[C@H]4CC[C@]5([C@@H](C4)CC[C@@H]6[C@@H]5CC[C@]7([C@@]6(CC[C@@H]7C8=CC(=O)OC8)O)C)C)C)C)O)O

Classification CLP

Type de classification

Harmonisée

ATP insertion

CLP00

Description de la classification

Classification harmonisée selon réglement 1272/2008 ou CLP

Mentions de danger
Mention du danger - Code H301
Mention du danger - Texte Toxique en cas d'ingestion
Classe(s) de dangers Toxicité aiguë
Libellé UE du danger -
Mention du danger - Code H331
Mention du danger - Texte Toxique par inhalation
Classe(s) de dangers Toxicité aiguë
Libellé UE du danger -
Limites de concentration spécifique -
Facteur M -
Estimation de toxicité aigüe -
Fiche ECHA
Fiche ECHA

Valeurs accidentelles

Autres seuils accidentels

Autres seuils accidentels
Nom Durée Valeur Source Etat du statut Commentaire
PAC-1 60 min 0,016 mg.m-3 EHSS (2018) Final
TEEL-2/11, LOC, rat oral LD50
PAC-2 60 min 0,18 mg.m-3 EHSS (2018) Final
TEEL-2/11, LOC, rat oral LD50
PAC-3 60 min 15 mg.m-3 EHSS (2018) Final
TEEL-2/11, LOC, rat oral LD50
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