Identification

Numero CAS

81-81-2

Nom scientifique (FR)

warfarine

Nom scientifique (EN)

4-hydroxy-3-(3-oxo-1-phenylbutyl)chromen-2-one

Autres dénominations scientifiques (FR)

Coumadin; Coumafène; (Phényl-1 acétyl-2 éthyl) 3-hydroxy-4 coumarine

Autres dénominations scientifiques (Autre langues)

warfarine ; 4-hydroxy-3-(3-oxo-1-phénylbutyl)coumarine ; 3-(alpha-acetonylbenzyl)-4-hydroxycoumarin ; 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2h-1-benzopyran-2-one ; 1-(4'-hydroxy-3'-coumarinyl)-1-phenyl-3-butanone ; 2h-1-benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)- ; 3-(1'-phenyl-2'-acetylethyl)-4-hydroxycoumarin ; 3-(acetonylbenzyl)-4-hydroxycoumarin ; 3-(alpha-acetonylbenzene)-4-hydroxycoumarin ; 3-(alpha-phenyl-beta-acetylaethyl)-4-hydroxycumarin ; 4-hydroxy-3-(3-oxo-1-fenyl-butyl) cumarine ; 4-hydroxy-3-(3-oxo-1-phenyl butyl)-2h-1-benzopyran-2-one ; 4-idrossi-3-(3-oxo-)-fenil-butil)-cumarine ; 3-(alpha-acetonylbenzyl)-4-hydroxy- ; coumarin, 4-hydroxy-3-(1-phenyl-3-oxobutyl)

Code EC

201-377-6

Code SANDRE

2972

Number CIPAC

-

Formule chimique brute

\(\ce{ C19H16O4 }\)

Code InChlKey

PJVWKTKQMONHTI-UHFFFAOYSA-N

Code SMILES

c1ccc2C(O)=C(C(c3ccccc3)CC(=O)C)C(=O)Oc2c1

CLP classification

Type de classification

Harmonisée

ATP insertion

CLP00/ATP09

Description de la classification

Classification harmonisée selon réglement 1272/2008 ou CLP

Hazard statements
Hazard statement - Code H300
Hazard statement - Text Mortel en cas d'ingestion
Hazard class(es) Toxicité aiguë
EU hazard label -
Hazard statement - Code H310
Hazard statement - Text Mortel par contact cutané
Hazard class(es) Toxicité aiguë
EU hazard label -
Hazard statement - Code H330
Hazard statement - Text Mortel par inhalation
Hazard class(es) Toxicité aiguë
EU hazard label -
Specific concentration limits Repr. 1A;H360D: C ≥ 0,003 %
STOT RE 1;H372: C ≥ 0,5 %
STOT RE 2;H373: ,05 % ≤ C < 0,5 %
M factor -
Acute toxicity estimate -
ECHA sheet
ECHA sheet

Regulations

Parameters table

Parameters table
Value name Value Temperature Pressure Granulometry Humidity Guideline ineris method Commentary Source
Coefficient de partage octanol/eau (Log Kow) 0.7 - Expérimentation ESIS (2011)
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Matrixes

Terrestrial environment

Parameters table
Value name Value Temperature Pressure Granulometry Humidity Guideline ineris method Commentary Source
Coefficient de partage carbone organique/Eau (Koc) 2.96 L.kg-1 Expérimentation Opasnet contributors
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Bioaccumulation

Aquatic organisms

Organismes aquatiques
ineris name Specie Value Trofic level Taxon Matrix Life stage Effect Detailed effect Duration of exposure ineris method Guideline Commentary Source
Bioaccumulation BCF 28.08 - Calcul EPA
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Accidental values

Other accidental thresholds

Other accidental thresholds
ineris name Duration Value Source Status state Commentary
IDLH 30 min 100 mg.m-3 NIOSH (1994) Final
PAC-1 60 min 1,8 mg.m-3 EHSS (2018) Final
TEEL-2/11, LOC, IDLH (1990)
PAC-2 60 min 20 mg.m-3 EHSS (2018) Final
TEEL-2/11, LOC, IDLH (1990)
PAC-3 60 min 350 mg.m-3 EHSS (2018) Final
TEEL-2/11, LOC, IDLH (1990)
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Regulatory values

Valeurs réglementaires
ineris name Value Source Commentary Critical effect retained Status state Duration of exposure Environment Exposure source Factor Management context Age-Dependent Adjustments Factors ADAF - Age range ADAF - Value ADAF - URL
VLEP 8h 0,1 mg.m-3 INRS (2024)
Valeur limite admise (circulaire)
Final Air Lieux de travail
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Reference values

Other values of recognized organizations

Autres valeurs des organismes reconnus
ineris name Value Source Commentary Critical effect retained Status state Duration of exposure Environment Exposure source Factor Management context Age-Dependent Adjustments Factors ADAF - Age range ADAF - Value ADAF - URL
RfD 0,0003 mg.kg-1.j-1 US EPA (1987) Increased prothrombin time Final Eau
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