Identification

Numero CAS

148-79-8

Nom scientifique (FR)

Thiabendazole

Nom scientifique (EN)

4-(1H-benzimidazol-2-yl)-1,3-thiazole

Autres dénominations scientifiques (FR)

2-(1,3-Thiazol-4-yl)-1H-benzimidazole

Autres dénominations scientifiques (Autre langues)

2-(1,3-thiazol-4-yl)-1H-1,3-benzodiazole ; 2-(thiazole-4-yl)benzimidazole ; thiabendazole ; 2-(4-Thiazolyl)-1H-benzimidazol (Thiabendazol) ; 2-Thiazol-4-yl-1H-benzoimidazool (thiabendazool) ; 2-tiazol-4-il-1H-benzoimidazolas (Tiabendazolas)

Code EC

205-725-8

Code SANDRE

1713

Number CIPAC

-

Formule chimique brute

\(\ce{ C10H7N3S }\)

Code InChlKey

WJCNZQLZVWNLKY-UHFFFAOYSA-N

Code SMILES

c2ccc1nc(nc1c2)c3cscn3

CLP classification

Type de classification

Harmonisée

ATP insertion

CLP00/ATP14

Description de la classification

Classification harmonisée selon réglement 1272/2008 ou CLP

Hazard statements
Hazard statement - Code H400
Hazard statement - Text Très toxique pour les organismes aquatiques
Hazard class(es) Danger pour le milieu aquatique
EU hazard label -
Hazard statement - Code H410
Hazard statement - Text Très toxique pour les organismes aquatiques, entraîne des effets à long terme
Hazard class(es) Danger pour le milieu aquatique
EU hazard label -
Specific concentration limits -
M factor M=1
M=1
Acute toxicity estimate -
ECHA sheet
ECHA sheet

Regulations

Generalities

Poids moléculaire

201.30 g/mol

Parameters table

Parameters table
Value name Value Temperature Pressure Granulometry Humidity Guideline ineris method Commentary Source
Hydrosolubilité 160 mg.L-1
à 20°C pH 4
EFSA (2013)
Hydrosolubilité 30 mg.L-1
à 20°C pH 9
EFSA (2013)
Hydrosolubilité 60 mg.L-1
à 20°C pH 7
EFSA (2013)
Constante de dissociation (pKa) 2.5 -
Dépend de la protonation du benzimidazole nitrogens et du thiazolyl nitrogen
EFSA (2013)
Constante de dissociation (pKa) 4.7 -
Dépend de la protonation du benzimidazole nitrogens et du thiazolyl nitrogen
EFSA (2013)
Pression de vapeur 5.3e-07 Pa
à 25°C
EFSA (2013)
Constante de Henry 3.7e-06 Pa.m3.mol-1
Volatilisation peu significative
EFSA (2013)
Coefficient de partage octanol/eau (Log Kow) 2.47 -
à 20°C pH 7
EFSA (2013)
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Matrixes

Terrestrial environment

Parameters table
Value name Value Temperature Pressure Granulometry Humidity Guideline ineris method Commentary Source
Coefficient de partage carbone organique/Eau (Koc) 2090 L.kg-1
soit log Koc = 3.3
EFSA (2013)
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Persistence

Biodegradability

Parameters table
Value name Value Temperature Pressure Granulometry Humidity Guideline ineris method Commentary Source
Biodégradabilité non facilement biodégradable -
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Bioaccumulation

Aquatic organisms

Organismes aquatiques
ineris name Specie Value Trofic level Taxon Matrix Life stage Effect Detailed effect Duration of exposure ineris method Guideline Commentary Source
Bioaccumulation BCF 96 -
BCF utilisé dans la détermination des normes de qualité
EFSA (2013)
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Reference values

Other values of recognized organizations

Autres valeurs des organismes reconnus
ineris name Value Source Commentary Critical effect retained Status state Duration of exposure Environment Exposure source Factor Management context Age-Dependent Adjustments Factors ADAF - Age range ADAF - Value ADAF - URL
ARfD 0,1 mg.kg-1pc AGRITOX (2022) Final Eau
ARfD 1 mg.kg-1pc OMS JMPR (2006) Final Eau
ARfD 0,3 mg.kg-1pc OMS JMPR (2006) Final Eau
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Hazards

Hazard values

Valeurs de danger
ineris name Specie Value Trofic level Taxon Matrix Life stage Effect Detailed effect Duration of exposure ineris method Guideline Commentary Source
CL/CE50 Pseudokirchneriella subcapitata 3.3 mg.L-1 Algue INERIS (2019)
CL/CE50 Daphnia magna 0.31 mg.L-1 Invertebré INERIS (2019)
CL/CE50 Oncorhynchus mykiss 0.55 mg.L-1 Poisson EFSA (2013)
CL/CE50 Americamysis bahia 0.34 mg.L-1 Invertebré INERIS (2019)
CL/CE50 Cyprinodon variegatus >10 mg.L-1 Poisson INERIS (2019)
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Ecotoxicological values

Guide values

Valeurs guides
ineris name Value Matrix Target Critical effect retained Duration of exposure Factor Commentary Status state Value retained by INERIS Year Source
Valeur guide eau 0.1 µg.L-1 Eau douce
Eau destinée à la production d'eau potable
Yes 2019 INERIS (2019)
Valeur guide eau 1.2 µg.L-1 Eau douce
Eau non destinée à la production d'eau potable
Yes 2019 INERIS (2019)
Valeur guide eau 0.12 µg.L-1 Eau marine Yes
Valeur guide sed 0.0115 mg.kg-1 (poids hum) Eau douce Yes 2019 INERIS (2019)
Valeur guide sed 0.03 mg/kg (poids sec) Eau douce Yes 2019 INERIS (2019)
Valeur guide sed 0.00115 mg.kg-1 (poids hum) Eau marine Yes 2019 INERIS (2019)
Valeur guide sed 0.003 mg/kg (poids sec) Eau marine Yes 2019 INERIS (2019)
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Regulatory values

Valeurs réglementaires
ineris name Value Matrix Target Critical effect retained Duration of exposure Factor Commentary Status state Value retained by INERIS Year Source
MAC 5 µg.L-1 Eau douce Yes 2019 INERIS (2019)
MAC 0.5 µg.L-1 Eau marine Yes 2019 INERIS (2019)
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