Identification

Numero CAS

822-06-0

Nom scientifique (FR)

Diisocyanate d'hexaméthylène

Nom scientifique (EN)

1,6-diisocyanatohexane

Autres dénominations scientifiques (FR)

1,6-Diisocyanate d'hexaméthylène

Autres dénominations scientifiques (Autre langues)

1,6-diisocyanatohexane ; hexamethylene diisocyanate ; hmdi ; 1,6-hexamethylene diisocyanate ; 1,6-hexanediol diisocyanate ; 1,6-hexylene diisocyanate ; hexamethylene-1,6-diisocyanate ; hexane, 1,6-diisocyanato- ; isocyanic acid, diester with 1,6-hexanediol ; isocyanic acid, hexamethylene ester ; metyleno-bis-fenyloizocyjanian ; szesciometylenodwuizocyjanian

Code EC

212-485-8

Code SANDRE

-

Number CIPAC

-

Formule chimique brute

\(\ce{ C8H12N2O2 }\)

Code InChlKey

RRAMGCGOFNQTLD-UHFFFAOYSA-N

Code SMILES

O=C=NCCCCCCN=C=O

CLP classification

Type de classification

Harmonisée

ATP insertion

CLP00

Description de la classification

Classification harmonisée selon réglement 1272/2008 ou CLP

Hazard statements
Hazard statement - Code H331
Hazard statement - Text Toxique par inhalation
Hazard class(es) Toxicité aiguë
EU hazard label -
Specific concentration limits Resp. Sens. 1;H334: C ≥ 0,5 %
Skin Sens. 1;H317: C ≥ 0,5 %
M factor -
Acute toxicity estimate -
ECHA sheet
ECHA sheet

Regulations

Generalities

Poids moléculaire

168.20 g/mol

Parameters table

Parameters table
Value name Value Temperature Pressure Granulometry Humidity Guideline ineris method Commentary Source
Densité 1.05 - UNEP (2004) p.20
Pression de vapeur 0.7 Pa
à 20°C
UNEP (2004) p.20
Point de fusion -67 °C UNEP (2004) p.20
Options
Download Display full table
This is a preview

This table has too many entries to display it completely. For a full display, use one of the options above.

Bibliography

Persistence

Biodegradability

Parameters table
Value name Value Temperature Pressure Granulometry Humidity Guideline ineris method Commentary Source
Biodégradabilité intrinsèquement biodégradable -
Options
Download Display full table
This is a preview

This table has too many entries to display it completely. For a full display, use one of the options above.

Abiotic degradability

Parameters table
Value name Value Temperature Pressure Granulometry Humidity Guideline ineris method Commentary Source
Photolyse 2.02 jour
calculée avec AOPWIN
UNEP (2004) p.20
Options
Download Display full table
This is a preview

This table has too many entries to display it completely. For a full display, use one of the options above.

Bibliography

Accidental values

Other accidental thresholds

Other accidental thresholds
ineris name Duration Value Source Status state Commentary
PAC-1 60 min 0,018 ppm EHSS (2018) Final
TEEL-2/11, REL-C (adjusted based on the ratio to toxicity data), rat 240-min LC50
PAC-2 60 min 0,2 ppm EHSS (2018) Final
TEEL-2/11, REL-C (adjusted based on the ratio to toxicity data), rat 240-min LC50
PAC-3 60 min 3 ppm EHSS (2018) Final
TEEL-2/11, REL-C (adjusted based on the ratio to toxicity data), rat 240-min LC50
Options
Download Display full table
This is a preview

This table has too many entries to display it completely. For a full display, use one of the options above.

Regulatory values

Valeurs réglementaires
ineris name Value Source Commentary Critical effect retained Status state Duration of exposure Environment Exposure source Factor Management context Age-Dependent Adjustments Factors ADAF - Age range ADAF - Value ADAF - URL
VLEP CT 0,02 ppm INRS (2024)
Valeur limite admise (circulaire)
Final Air Lieux de travail
VLEP CT 0,15 mg.m-3 INRS (2024)
Valeur limite admise (circulaire)
Final Air Lieux de travail
Options
Download Display full table
This is a preview

This table has too many entries to display it completely. For a full display, use one of the options above.

Reference values

Other values of recognized organizations

Autres valeurs des organismes reconnus
ineris name Value Source Commentary Critical effect retained Status state Duration of exposure Environment Exposure source Factor Management context Age-Dependent Adjustments Factors ADAF - Age range ADAF - Value ADAF - URL
REL 0,3 µg.m-3 OEHHA (2019)
HDI monomer
Nasal epithelium lesions in rodents Final Acute REL (for a 1-hour exposure) Air ambiant
REL 0,06 µg.m-3 OEHHA (2019)
HDI monomer
HDI-induced asthma accelerated decline in lung function in humans Final 8-Hour REL (for repeated 8-hour exposure) Air ambiant
REL 4,5 µg.m-3 OEHHA (2019)
HDI polyisocyanate
Increased total protein in pulmonary region of rodents Final Acute REL (for a 1-hour exposure) Air ambiant
REL 0,8 µg.m-3 OEHHA (2019)
HDI polyisocyanate
Pulmonary inflammation and fibrosis in rodents Final 8-Hour REL (for repeated 8-hour exposure) Air ambiant
Options
Download Display full table
This is a preview

This table has too many entries to display it completely. For a full display, use one of the options above.

Bibliography

Hazards

Hazard values

Valeurs de danger
ineris name Specie Value Trofic level Taxon Matrix Life stage Effect Detailed effect Duration of exposure ineris method Guideline Commentary Source
CL/CE50 >77.4 mg.L-1 Algue UNEP (2004) p.20
Options
Download Display full table
This is a preview

This table has too many entries to display it completely. For a full display, use one of the options above.

Ecotoxicological values

Guide values

Valeurs guides
ineris name Value Matrix Target Critical effect retained Duration of exposure Factor Commentary Status state Value retained by INERIS Year Source
PNEC chronique / AA-QSwater_eco 0.0774 mg.L-1 Eau douce 1000
Les tests d'ecotoxicité ont été réalisés avec les produits de l'hydrolyse de cette substance à cause de son hydrolyse très rapide. - extrapolation
Yes UNEP (2004) p.20
Options
Download Display full table
This is a preview

This table has too many entries to display it completely. For a full display, use one of the options above.

Bibliography

Export substance

Choose the format of the export :