Toxicologie > Valeurs de référence > Autres valeurs des organismes reconnus
Last update the 01/07/2025| Target | Exposure route | Effect type | Exposure type | Value name | Value | Source | Commentary | Critical effect retained | Status state | Exposure duration | Environment | Exposure source | Factor | Management context | Age dependent adjustments factors | ADAF - Age range | ADAF - Value | ADAF - URL |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Population générale | Inhalation | A seuil | Aiguë | MRL | 0,1 ppm | ATSDR (2024) | 0.5 mg/m3 |
Increased methemoglobin | Final | Air ambiant | 30 | |||||||
| Population générale | Inhalation | A seuil | Chronique | MRL | 0,0002 ppm | ATSDR (2024) | 0.001 mg/m3 |
Hyperplasia of the nasal squamous epithelium | Final | Air ambiant | 300 | |||||||
| Population générale | Inhalation | A seuil | Sub-chronique | MRL | 0,003 ppm | ATSDR (2024) | 0.02 mg/m3 |
Hematological, renal, hepatic, and endocrine effects | Final | Air ambiant | 300 | |||||||
| Population générale | Orale | A seuil | Aiguë | MRL | 0,05 mg.kg-1.j-1 | ATSDR (2024) | Proliferative changes in the bone marrow | Final | 100 | |||||||||
| Population générale | Orale | A seuil | Sub-chronique | MRL | 0,02 mg.kg-1.j-1 | ATSDR (2024) | Increased methemoglobin | Final | 100 | |||||||||
| Population générale | Orale | A seuil | Chronique | MRL | - - | ATSDR (2024) | Il n’existe pas suffisamment de données pour justifier la dérivation d’une MRL orale de durée chronique |
- | Final | - | ||||||||
| Population générale | Inhalation | A seuil | Chronique | RfC | 0,009 mg.m-3 | US EPA (2009) | Bronchiolization of the alveoli and olfactory degeneration | Final | Air ambiant | |||||||||
| Population générale | Inhalation | Sans seuil | Chronique | Inhalation Unit Risk | 0,00004 (µg.m-3)-1 | US EPA (2009) | Liver hepatocellular adenomas or carcinomas, kidney tubular adenomas or carcinomas, thyroid follicular cell adenomas or carcinomas | Final | Air ambiant | |||||||||
| Population générale | Orale | A seuil | Chronique | RfD | 0,002 mg.kg-1.j-1 | US EPA (2009) | Increased methemoglobin levels | Final | Eau |